Bioimaging Core Facility
Bioimaging Core Facility Unit
Academic Coordinator:Dr George McKerr
Tel: +44 (0)28 7012 4759
The Bioimaging Core Facility at the University of Ulster is equipped with £5 million state-ofthe- art instrumentation and provides a unique opportunity for access to imaging modalities rarely found within a single laboratory. This includes all major variations of light and electron microscopy, confocal, two-photon, second harmonic generation, super resolution and probe microscopy as well as significant software solutions for deconvolution, three-dimensional reconstruction and the latest software from Explora Nova for the implementation of ‘one stop stereology’.
The facility has Reference Laboratory status on two fronts (EM and super resolution optical microscopy) and can provide expert assistance from factory-trained staff on manufacturer maintained and optimised microscopes. All instruments are comprehensively serviced and calibrated by manufacturers’ engineers and the lab has extensive collaborative links with global industries and over two decades of productive collaborations with instrument manufacturers and software developers
Stereo Zoom Microscopy
Custom imaging solutions.
Measurement of DNA damage e.g., comet assay
Multiple antigen detection
Quantitative analyses (eco-toxicology, cell based experiments, engineered tissues)
Preparation of full and confidential reports, e.g., patent protection, new product development and prototyping.
Laser dissection and manipulation
Sub-cellular and single micro-organism collection
Training and collaborative projects
Assistance with lead up to grant applications and proof of concept.
Cryo-Ultramicrotomy and Preparatory Techniques
Expert assistance with highly skilled techniques
Accurate imaging of sensitive structures in food, pharma and emulsions
Individually tailored preparation regimes
Comprehensive analysis of results.
Transmission Electron Microscopy
Support and innovation
Spatial analysis by tomography and reconstruction
Low electron dose imaging of fragile frozen samples
Imaging and counting of nano-particles.
Environmental Scanning Electron Microscopy
Novel imaging of hydrated specimens
Recording of dynamic events in gels and creams
Full access to trained partners
Workshops to update all customers.
Stimulated Emission Depletion (STED) Super Resolution
Brand new technology in superresolution
Ulster’s Leica Centre for tissue engineering, offers opportunities in numerous areas of life sciences, food production, pharmacology and nanomedicine
Dynamic imaging of delivery systems within cells and deep tissues in x, y, z and time (hours to days)
Cryo-Focused Ion Beam/Scanning Electron Microscopy
Unique access to market leading nanofabrication facility
Site specific modification of deep cooled samples
Partnership, in product testing and defect tracing.