Nano Systems Biology
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Dr Clifford Barnes

Research Associate in 3D Tissue Culture

Brief Profile

Clifford Barnes graduated from the University of Ulster in 2003 with a BSc (Hons) in Biomedical Science and a Diploma in Industrial Science. He completed his PhD in 2007 entitled "Supra-Vital Atomic Force Microscopy of Living Cultured Cells." This work involved creating an imaging environment whereby cells could be imaged in physiological conditions whilst monitoring intracellular ion activity. Using functionalised AFM tip techniques Clifford successfully imaged the locations and bonding strengths of the epidermal growth factor receptor in human lung cancer cells where the over-expression of this important receptor is a characteristic of certain cancers. Clifford then became employed as a research associate under a 3 year contract in the European NanoInteract Project, headed by Professor Howard and Dr George McKerr. He is currently employed as a research associate in work funded by NC3Rs involving 3D cell culture.

Current Research

Clifford’s current interests involve the development of a human breast tissue model using 3D cell culture techniques. Using a range of microscopical techniques Clifford carries out long term imaging of living cells in collagen gels as they form complex structures over a period of days and in some cases weeks.

Dr Clifford Barnes


Dr Clifford Barnes - Publications