Nano Systems Biology
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Dr Kurt Saetzler

Lecturer in Computational Biology

Academic and Professional Qualifications
- 2000: PhD (Dr. rer. nat.) in Physics, University of Heidelberg , Germany
- 1995: MSc (Diplom) in Physics, University of Heidelberg , Germany

Career History
- 2003 - present: Lecturer in Computational Biology, University of Ulster, Coleraine
- 2000 - 2003: Postdoctoral Research Fellow, Max Planck Institute for Medical Research, Germany
- 1999 - 2001: Research Associate, German Cancer Research Centre, Heidelberg, Germany
- 1995 - 1999: Research Associate, Heidelberg, Germany
- 1995 - 1995: Research Associate, Institute for Human genetics, Heidelberg, Germany
- 1992 - 1995: Research Assistant, Interdisciplinary Centre for Scientific Computing, Heidelberg, Germany

Teaching & Learning Activities

Module Co-ordinator for Statistics and Probabilistic Modelling in Bioinformatics (Bayesian statistics) as part of the PgDip/MSc programme in Bioinformatics.

Dr Kurt Saetzler


Dr Kurt Saetzler - Publications

Number of items: 43.

Rollenhagen, Astrid, Klook, Kerstin, Saetzler, Kurt, Qi, Guanxiao, Anstötz, Max, Feldmeyer, Dirk and Lübke, Joachim H R (2015) Structural determinants underlying the high efficacy of synaptic transmission and plasticity at synaptic boutons in layer 4 of the adult rat 'barrel cortex'. Brain Structure and Function, 220 (6). pp. 3185-3209.

Dufour, Amandine, Rollenhagen, Astrid, Saetzler, Kurt and Lübke, Joachim H R. (2015) Development of Synaptic Boutons in Layer 4 of the Barrel Field of the Rat Somatosensory Cortex: A Quantitative Analysis.. Cereb Cortex, 26 (2). pp. 838-854.

Barnes, Clifford, McKerr, George, Soto, A. M., Downes, Stephen, Howard, Vyvyan and Saetzler, Kurt (2014) From Single Cells to Tissues: Interactions between the Matrix and Human Breast Cells in Real Time. PLOS ONE, 9 (4). pp. 1-12.

Körber, Christoph, Horstmann, Heinz, Saetzler, Kurt and Kuner, Thomas (2012) Endocytic Structures and Synaptic Vesicle Recycling at a Central Synapse in Awake Rats.. Traffic, 13. pp. 1601â??1611.

Zhao, Shanting, Studer, Daniel, Chai, Xuejun, Graber, Werner, Brose, Nils, Nestel, Sigrun, Young, Christina, Rodriguez, E. Patricia, Saetzler, Kurt and Frotscher, Michael (2012) Structural plasticity of hippocampal mossy fiber synapses as revealed by high-pressure freezing.. J Comp Neurol, 520 (11). pp. 2340-2351.

Horstmann, Heinz, Körber, Christoph, Saetzler, Kurt, Aydin, Daniel and Kuner, Thomas (2012) Serial Section Scanning Electron Microscopy (S(3)EM) on Silicon Wafers for Ultra-Structural Volume Imaging of Cells and Tissues.. PLoS One, 7 (4). pp. e35172.

Zhang, Huaizhong, Morrow, PJ, McClean, SI and Saetzler, Kurt (2012) Coupling edge and region-based information for boundary finding in biomedical imagery. Pattern Recognition, 45 (2). pp. 672-684.

Zhao, Shanting, Studer, Daniel, Chai, Xuejun, Graber, Werner, Brose, Nils, Nestel, Sigrun, Young, Christina, Rodriguez, E. Patricia, Saetzler, Kurt and Frotscher, Michael (2012) Structural plasticity of spines at giant mossy fiber synapses. Frontiers in Neural Circuits, 6.

Saetzler, Kurt, Sonnenschein, C and Soto, A. M. (2011) Systems biology beyond networks: Generating order from disorder through self-organization.. Semin Cancer Biol, 21. pp. 165-174.

Busti, Daniela, Geracitano, Raffaella, Whittle, Nigel, Yannis, Dalezios, Manko, Miroslawa, Kaufmann, Walter, Saetzler, Kurt, Singewald, Nicolas, Capogna, Marco and Ferraguti, Francesco (2011) Different Fear States Engage Distinct Networks within the Intercalated Cell Clusters of the Amygdala.. J Neurosci, 31 (13). pp. 5131-5144.

Zhang, Huaizhong, Morrow, PJ, McClean, SI and Saetzler, Kurt (2010) A stability approach to convergence of curve evolution methods. Pattern Recognition Letters, 31 (13). pp. 1909-1918.

Konetschnig, J, Saetzler, Kurt and Elbischger, P (2010) A novel framework for Z-registration of electron microscopy image stacks. In: 34th Workshop of the Austrian Association for Pattern Recognition (AAPR/ÖAGM'10), Zwettl, Waldviertel, Austria. Österreichische Computer Gesellschaft (OCG). 89-96

Dondzillo, Anna, Saetzler, Kurt, Horstmann, Heinz, Altrock, Wilko D., Gundelfinger, Eckart D. and Kuner, Thomas (2010) Targeted three-dimensional immunohistochemistry reveals localization of presynaptic proteins Bassoon and Piccolo in the rat calyx of Held before and after the onset of hearing. Journal of Comparative Neurology, 518 (7). pp. 1008-1029.

McArt, DG, McKerr, George, Saetzler, Kurt, Howard, Vyvyan, Downes, Stephen and Wasson, GR (2010) Comet sensitivity in assessing DNA damage and repair in different cell cycle stages. Mutagenesis, 25 (3). pp. 299.

McArt, Darragh G, McKerr, G, Howard, Vyvyan, Saetzler, Kurt and Wasson, Gillian R (2009) Modelling the comet assay. Biochemical Society Transactions, 037 (4). pp. 914-917.

McArt, Darragh G, Wasson, Gillian R, McKerr, George, Saetzler, Kurt, Reed, Matt and Howard, Vyvyan (2009) Systematic random sampling of the comet assay. Mutagenesis, 24 (4). pp. 373-378.

Saetzler, Kurt, McCanny, P., Rodriguez, E.P., and R.M. Bruno, H. Horstmann and Denk, W. (2009) A fuzzy algorithm to trace stained neurons in serial block-face scanning electron microscopy image series. In: 13th International Machine Vision and Image Processing Conference, Dublin. . 162-167

Zhang, Huaizhong, Rodriguez, E. Patricia, Morrow, Philip, McClean, Sally and Saetzler, Kurt (2009) MCMC-based algorithm to adjust scale bias in large series of electron microscopical ultrathin sections. In: Proceedings of the 13th International Conference on Computer Analysis of Images and Patterns. . 557-564

Zhang, Huaizhong, Morrow, PJ, McClean, S and Saetzler, Kurt (2008) Contour detection of labeled cellular structures from serial ultrathin electron microscopy sections using GAC and prior analysis. In: IEEE Proceedings of IPTA'08. . 317-323

Guerreiro-Lucas, Luciano A, Pop, S. Rares, Ma, Maria J C Machado and Ying Liang, Waters, Sarah L, Richardson, Giles, Saetzler, Kurt, Jensen, Oliver E and Mitchell, Christopher (2008) Experimental and theoretical modelling of blind-ended vessels within a developing angiogenic plexus.. Microvasc Res, 76. pp. 161-168.

Ma, YingLiang and Saetzler, Kurt (2008) A Parallelized Surface Extraction Algorithm for Large Binary Image Data Sets Based on an Adaptive 3-D Delaunay Subdivision Strategy. IEEE Transactions on Visualization and Computer Graphics, 14 (1). pp. 160-172.

Ma, Ying Liang, Rhode, Kawal S., King, Andy P., Phani Chinchapatnam, Gang Gao, Schaeffter, Tobias, Razavi, Reza and Saetzler, Kurt (2008) Time-varying Image Data Visualization Framework for Application in Cardiac Catheterization Procedures. In: Theory and Practice of Computer Graphics, Manchester. . 137-140

Ma, Y.L., Rhode, K.S., Razavi, R. and Saetzler, Kurt (2008) Real-Time Visualization of Cardiac Catheterization Procedures Based on a New Algorithm for Reconstructions from Planar Cross Sections Using the Unconstrained 3D Delaunay Triangulation. In: Proc. International Machine Vision and Image Processing Conference IMVIP '08, Coleraine. . 142-147

Rollenhagen, Astrid, Saetzler, Kurt, Rodriguez, E Patricia, Jonas, Peter, Frotscher, Michael and Lübke, Joachim H. R. (2007) Structural Determinants of Transmission at Large Hippocampal Mossy Fiber Synapses. J. Neurosci., 27 (39). pp. 10434-10444.

Morrow, PJ and Saetzler, Kurt (2007) Validation of in vivo Leukocyte Velocity Estimates via Modeling and Simulation. In: Conference Record of the Forty-First Asilomar Conference on Signals, Systems and Computers ACSSC 2007, Pacific Groove. . 1288-1292

Bigot, S., Lucas, L., Morrow, PJ, Mitchell, Christopher and Saetzler, Kurt (2007) Estimating leukocyte velocities from high-speed 1D line scans oriented orthogonal to blood flow. In: Biomedical Imaging: Macro to Nano, 2007. 4rd IEEE International Symposium on, Washington. . 376-379

Zhang, Huaizhong, Morrow, Philip, McClean, Sally and Saetzler, Kurt (2007) Incorporating Feature Based Priors into the Geodesic Active Contour Model and its Application in Biomedical Imagery. In: Proc. of the International Machine Vision and Image Processing Conference, 2007. IMVIP 2007.. . 67-74

Bigot, Stephane, Lucas, Luciano, Morrow, Philip, Mitchell, Christopher and Saetzler, Kurt (2007) Estimating leukocyte velocities from high-speed 1D line scans oriented orthogonal to blood flow. In: 2007 4TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING : MACRO TO NANO, VOLS 1-3. ISBI. 376-379

McEnery, O., Lucas, L., Ma, YingLiang, Morrow, PJ, Mitchell, Christopher and Saetzler, Kurt (2006) A fast, robust and scale-independent approach to estimate vessel diameters in intravital fluorescence microscopy images. In: Biomedical Imaging: Macro to Nano, 2006. 3rd IEEE International Symposium on. . 101-104

Saetzler, Kurt, Söhl, Leander F, Bollmann, Johann H, Borst, J. Gerard G, Frotscher, Michael, Sakmann, Bert and Lübke, Joachim H R (2002) Three-dimensional reconstruction of a calyx of Held and its postsynaptic principal neuron in the medial nucleus of the trapezoid body.. J Neurosci, 22 (24). pp. 10567-10579.

Saetzler, Kurt (2001) 3-D Rekonstruktion von Serienschnitten. In: Forschung und wissenschaftliches Rechnen, Beiträge zum Heinz-Billing-Preis 2000. (Eds: Plesser, T. and Hayd, H.), GWDG, pp. 31-47. ISBN 0176-2516

Grabenbauer, M., Saetzler, Kurt, Baumgart, E. and Fahimi, H.D. (2000) Three-dimensional ultrastructural analysis of peroxisomes in HepG2 cells: Absence of a peroxisomal reticulum but evidence of close spatial association with the endoplasmic reticulum.. Cell. Biochem. Biophys., 32. pp. 37-49.

Saetzler, Kurt (2000) 3D--Rekonstruktion von elektronenmikroskopischen Serienschnitten.

Saetzler, Kurt (2000) 3D Rekonstruktion von Serienschnitten mit CAR.

Eils, R. and Saetzler, Kurt (1999) Shape Reconstruction from Volumetric Data. In: Handbook of Computer Vision and Applications. (Eds: Jähne, B., Haußecker, H. and Geißler, P.), Academic Press, San Diego, London, Boston, New York, Sydney, Tokyo, Toronto, pp. 791-815. ISBN 0123797705

Eils, R., Saracoglu, K. and Saetzler, Kurt (1999) Morphological parameters, medial lines and skeletons computed in the 3D--Voronoi diagram with applications to 3D CLSM images. In: Focus on Multidimensional Microscopy. (Eds: Cheng, P.C., Hwang, P.P., Wu, J.L., Wang, G. and Kim, H.), World Scientific Publishing, Singapore, pp. 34-56. ISBN 9810239920

Dietzel, S., Eils, R., Saetzler, Kurt, Bornfeld, H., Jauch, A., Cremer, C. and Cremer, T. (1998) Evidence against a looped structure of the inactive human X--chromosome territory. Exp. Cell Res, 240 (2). pp. 187-196.

Bornfleth, H., Saetzler, Kurt, Elis, R. and Cremer, C. (1998) High-precision distance measurements and volume-conserving segmentation of objects near and below the resolution limit in three-dimensional confocal fluorescence microscopy. Journal of Microscopy, 189. pp. 118-136.

Eils, R., Uhrig, S., Saetzler, Kurt, Saracoglu, K., Chassery, A. Bolzer and J.-M., Ganser, M. and Speicher, M.R. (1998) An optimized and fully automated system for fast and accurate identification of chromosomal rearrangements my multiplex-FISH (M-FISH). Cell Genetics and Cytogenetics, 82. pp. 160-171.

Saetzler, Kurt and Eils, R. (1997) Resolution improvement by 3-D reconstructions from tilted views in axial tomography and confocal theta microscopy. Bioimaging, 5. pp. 171-182.

Bornfleth, H., Zink, D., Saetzler, Kurt, Eils, R. and Cremer, C. (1996) Modellgestützte Segmentierung von Replikationsdomänen in dreidimensionalen konfokalen Mikroskopiebildern. In: Mustererkennung 1996. . 408-419

Saetzler, Kurt, Cremer, Cornelius and Eils, Roland (1996) 3D-Bildfolgen zur Auflösungsverbesserung in der Fluoreszenzmikroskopie. In: Mustererkennung 1996, 18. DAGM-Symposium. . 92-105

Eils, R., Saracoglu, K., Münkel, C., Imhoff, J., Saetzler, Kurt, Dietzel, S., Schröck, E., Ried, T., Cremer, T. and Cremer, C. (1995) Three--dimensional imaging approaches and Monte Carlo simulations: development of tools to study the morphology and distribution of chromosome territories and subchromosomal targets in human cell nuclei. In: Zoological Studies. . 7-10

This list was generated on Sat Jun 24 13:16:46 2017 BST.