Nano Systems Biology
  1. Background
  2. Contact
  3. Publications

Professor Werner Dubitzky

Professor of Bioinformatics

Academic and Professional Qualifications

- 1991: MSc Electrical Engineering, FH Augsburg, Augsburg, Germany
- 1997: PhD Artificial Intelligence, University of Ulster

Career History

- Professor of Bioinformatics, University of Ulster
- Head of Data Mining Group, German Cancer Research Center
- Lecturer, University of Ulster
- Research Fellow, University of Ulster

Short Biography

I was awarded an MSc in electrical and communication engineering from the Augsburg University of Applied Science, Germany, in 1991 and a Ph.D. in artificial intelligence and machine learning from the University of Ulster, Northern Ireland, UK, in 1997.

From January 2000 to December 2001 I spearheaded the data mining developments at the Intelligent Bioinformatics Systems Group at the German Cancer Research Center, Heidelberg, Germany. Since 2002 I hold the Chair of Bioinformatics at the Biomedical Sciences Research Institute, Faculty of Life and Health Science, at the University of Ulster at Coleraine, Northern Ireland, UK.

You find a detailed curriculum vitae here

Teaching & Learning Activities

MSc in Systems Biology (100% online course)

Apply here:

This course is designed for students and researchers with a life science background wanting to learn more about the formal concepts and tools facilitating the modeling, analysis and simulation of biological systems.

Aims/audience: Equip learners with conceptual and practical knowledge of the methods and tools of systems biology. Emphasis is placed on solving concrete problems based on the programming language R. No prior programming knowledge is required, as R programming is fully covered in the course.

Content/structure: The MSc consists of 8 taught modules (15 credit points each) plus a research project worth 60 credit points. It is also possible to exit with a PgCert award after completion of 4 modules and a PgDip award after eight modules.

Content delivery: Fully online. Each module is assessed 100% by coursework/assignments (online discussions, coursework, essays, etc.). There is no requirement to be on campus.

Registration: In principle, registration is open untilSeptember 2014. If you make sure to get a place, it is better to apply sooner. If in doubt, please contact me.,

Contact: Professor Werner Dubitzky.
- Email:
- Phone: +44 7739 723 424 (mobile, WhatsApp)
- Phone: +44 28 70124478 (office)
- Skype: grobgestein

Prospectus: Formal details (including fees) are found in the Ulster Prospectus.

Course Leaflet: (PDF)

Facebook: Join us on Facebook and like our Facebook Page:

Research Activities and Interests

Call for papers for special issue in Briefings in Bioinformatics on Computational Systems Biomedicine. Call for papers: PDF

Call for papers for special issue in Computation (open access journal) on Multiscale Modeling and Simulation in Computational Biology. Notice, manuscripts will be published in the journal’s regular issues as soon as they are accepted by the peer-review process. More

My current research interests are in the area of multiscale modelling and simulation in biology (see the MAPPER project) and reverse-engineering of gene-regulation network models. A main challenge in reverse-engineering is the inference of reliable mechanistic network structure (as opposed to producing a good dynamic response to new input data) from gene expression data.

I have published my Google Scholar citations here


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Professor Werner Dubitzky


Professor Werner Dubitzky
Professor of Bioinformatics
Biomedical Sciences Research Institute


Room W1019
School of Biomedical Sciences
University of Ulster
Coleraine campus
Cromore Road
Co. Londonderry
BT52 1SA

phone: +44 28 70124478

Professor Werner Dubitzky - Publications

Number of items: 29.

Borgdorff , J., Belgacem , M.B., Bona-Casas , C., Fazendeiro , L., Groen , D., Hoenen , O., Mizeranschi , A., Suter , J.L., Coster , D., Coveney, P.V., Dubitzky, Werner, Hoekstra , A.G., Strand , P. and Chopard , B. (2014) Performance of distributed multiscale simulations. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 372 (221).

Kennedy, Noel, Mizeranschi, Alexandru, Thompson, Paul, Zheng, Huiru and Dubitzky, Werner (2013) Reverse engineering of gene regulation models from multi-condition experiments. In: Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), 2013 IEEE Symposium on. IEEE. 112-119

Wang, Chong, Beyerlein, Peter, Pospisil, Heike, Krause, Antje, Nugent, Chris D and Dubitzky, W (2012) An Efficient Method for Modeling Kinetic Behavior of Channel Proteins in Cardiomyocytes. IEEE/ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS,, 9 (1). pp. 40-51.

Swain, Martin T, Mandel, Johannes J and Dubitzky, Werner (2010) Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks. BMC Bioinformatics, 11 (459).

Swain, Martin, Silva, Cândida, Loureiro-Ferreira, Nuno, Ostropytskyy, Vitaliy, Brito, João, Riche, Olivier, Stahl, Frederick, Dubitzky, Werner and Brito, Rui M M (2010) P-found: Grid-enabling distributed repositories of protein folding and unfolding simulations for data mining. Future Generation Computer Systems, 26 (3). pp. 424-433.

Hill, T. R., Cotter, A. A., Mitchell, S., Boreham, C. A., Dubitzky, W, Murray, L., Strain, JJ, Flynn, A., Robson, P. J., Wallace, Julie, Kiely, M. and Cashman, K. D. (2010) Vitamin D status and parathyroid hormone relationship in adolescents and its association with bone health parameters: analysis of the Northern Ireland Young Heart’s Project. Osteoporosis International, 21 (4). pp. 695-700.

Stankovski, Vlado, Trnkoczy, Jernej, Swain, Martin, Dubitzky, Werner, Kravtsov, Valentin, Schuster, Assaf, Niessen, Thomas, Wegener, Dennis, May, Michael, Röhm, Matthias and Franke, Jürgen (2008) Digging Deep into the Data Mine with DataMiningGrid. IEEE INTERNET COMPUTING, 12 (6). pp. 69-76.

Hill, Tom R., Cotter, Alice A., Mitchell, Sarah, Boreham, Colin A., Dubitzky, W, Murray, Liam, Strain, JJ, Flynn, Albert, Robson, Paula J., Wallace, Julie, Kiely, Mairead and Cashman, Kevin D. (2008) Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort. BRITISH JOURNAL OF NUTRITION, 99 (5). pp. 1061-1067.

Cashman, Kevin D., Hill, Tom R., Cotter, Alice A., Boreham, Colin A., Dubitzky, Werner, Murray, Liam, Strain, JJ, Flynn, Albert, Robson, Paula J., Wallace, Julie and Kiely, Mairead (2008) Low vitamin D status adversely affects bone health parameters in adolescents. AMERICAN JOURNAL OF CLINICAL NUTRITION, 87 (4). pp. 1039-1044.

Stankovski, Vlado, Swain, Martin, Kravtsov, Valentin, Niessen, Thomas, Wegener, Dennis, Kindermann, Joerg and Dubitzky, Werner (2008) Grid-enabling data mining applications with DataMiningGrid: An architectural perspective. FUTURE GENERATION COMPUTER SYSTEMS-THE INTERNATIONAL JOURNAL OF GRID COMPUTING THEORY METHODS AND APPLICATIONS, 24 (4). pp. 259-279.

Fuss, Hendrik, Dubitzky, Werner, Downes, Stephen and Kurth, Mary Jo (2008) Src family kinases and receptors: Analysis of three activation mechanisms by dynamic systems modeling. BIOPHYSICAL JOURNAL, 94 (6). pp. 1995-2006.

Wang, C, Beyerlein, P, Hammer, P, Krause, A, Nugent, C and Dubitzky, Werner (2008) Allosteric Interaction of Rapid Delayed Rectifier Protein and Its Role in Cardiac Repolarization. In: COMPUTERS IN CARDIOLOGY 2008, VOLS 1 AND 2, Bologna, Italy. . 589-592

Fuss, Hendrik, Dubitzky, Werner, Downes, Stephen and Kurth, Mary Jo (2007) Deactivation of src family kinases: Hypothesis testing using a Monte Carlo sensitivity analysis of systems-level properties. JOURNAL OF COMPUTATIONAL BIOLOGY, 14 (9). pp. 1185-1200.

Gilbert, David, Fuss, Hendrik, Gu, Xu, Orton, Richard, Robinson, Steve, Vyshemirsky, Vladislav, Kurth, Mary Jo, Downes, Stephen and Dubitzky, Werner (2006) Computational methodologies for modelling, analysis and simulation of signalling networks. BRIEFINGS IN BIOINFORMATICS, 7 (4). pp. 339-353.

Dubitzky, Werner, Berrar, Daniel and Hack, Catherine (2006) Text mining of full-text journal articles combined with gene expression analysis reveals a relationship between sphingosine-1-phosphate and invasiveness of a glioblastoma cell line. BMC Bioinformatics, 7. pp. 373.

Fuss, Hendrik, Dubitzky, Werner, Downes, Stephen and Kurth, Mary Jo (2006) Bistable switching and excitable behaviour in the activation of Src at mitosis. BIOINFORMATICS, 22 (14). pp. E158-E165.

Berrar, D, Bradbury, I and Dubitzky, Werner (2006) Avoiding model selection bias in small-sample genomic datasets. BIOINFORMATICS, 22 (10). pp. 1245-1250.

Berrar, D, Sturgeon, B, Bradbury, I, Downes, Stephen and Dubitzky, Werner (2005) Survival trees for analyzing clinical outcome in lung adenocarcinomas based on gene expression profiles: Identification of neogenin and diacylglycerol kinase alpha expression as critical factors. JOURNAL OF COMPUTATIONAL BIOLOGY, 12 (5). pp. 534-544.

Fuss, H, Dubitzky, Werner, Downes, Stephen and Kurth, MJ (2005) Mathematical models of cell cycle regulation. BRIEFINGS IN BIOINFORMATICS, 6 (2). pp. 163-177.

Wang, Hui and Dubitzky, Werner (2005) A flexible and robust similarity measure based on contextual probability. In: International Joint Conference on Artificial Intelligence , Edinburgh. . 27-32

Berrar, Daniel, Sturgeon, B, Bradbury, I, Downes, Stephen and Dubitzky, Werner (2005) Integration of microarray data for a comparative study of classifiers and identification of marker genes. In: METHODS OF MICROARRAY DATA ANALYSIS IV, Durham, NC. . 147-162

Berrar, Daniel, Hack, Catherine and Dubitzky, Werner (2005) Knowledge discovery in biology and biotechnology texts: a review of techniques, evaluation strategies, and applications.. Critical reviews in biotechnology, 25 (1-2). pp. 31-52.

Berrar, Daniel, Hack, Catherine and Dubitzky, W (2005) Knowledge Discovery in Biology and Biotechnology Texts: A Review of Techniques, Evaluation Strategies, and Applications. Critical Reviews in Biotechnology, 25 (1-2). pp. 31.

Bi, YX, Bell, D, Wang, H, Guo, GD and Dubitzky, Werner (2004) Classification decision combination for text categorization: An experimental study. In: DATABASE AND EXPERT SYSTEMS APPLICATIONS, PROCEEDINGS, Zaragoza, Spain. . 222-231

O'Donoghue, P, Dubitzky, W, Lopes, P, Berrar, D, Lagan, K, Hassan, D, Bairner, A and Darby, Paul (2004) An evaluation of qualitative and quantitative methods of predicting the 2002 FIFA World Cup. Journal of Sport Sciences, 22 (6). pp. 513-514.

Dubitzky, Werner and Azuaje, FJ (2003) AI in the life sciences. ARTIFICIAL INTELLIGENCE REVIEW, 20 (1-2). pp. 7-11.

Sturgeon, B, McCourt, D, Cowper, J, Palmer, FL, McClean, SI and Dubitzky, W (2003) Can the Grid Help to Solve the Data Integration Problems in Molecular Biology? . In: 3rd IEEE International Symposium on Cluster Computing and the Grid (CCGrid 2003), Tokyo, Japan. IEEE Computer Society. 594-600

Wang, Hui, Dubitzky, Werner, Duntsch, Ivo and Bell, David (1999) A lattice machine approach to automated casebase design: Marrying lazy and eager learning. In: International Joint Conference on Artificial Intelligence. . 254-259

Dubitzky, W, Mariotti, D, Hyland, M and McLaughlin, JAD (1998) A neural network approach to plasma emission interpretation. In: International Society for Computers and their Applications 11TH International Conference on Computer Applications in Industry and Engineering, Las Vegas, USA. . 47-50

This list was generated on Thu Apr 2 01:19:57 2015 BST.